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On the other hand, chlorpyrifos has shown the ability to overexpress the GST gene of the migratory locust, cotton leaf worm and rice plant hopper [36,37,38]

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Trx1 promotes reverse cholesterol transport (Figure 3) via nuclear translocation of liver X receptor and subsequent increase of ATP-binding cassette transporter A1 expression, thereby inhibiting hepatic steatosis [98] , a disease condition linked to ferroptosis [99]

doi: 10.1053/j.gastro.2021.07.008

First, a deeper investigation into ASTs molecular mechanisms in various chronic diseases is needed, especially regarding its targets and signaling pathways in neurodegenerative and metabolic disorders